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Virtual Cell User Documentation

User Guide, Quick Start and Tutorials


Release Notes

Current information on Release and Beta versions.


Technical Requirements
Hardware and software system specific requirements.


Modeling Links

Additional modeling sites

Run the Virtual Cell
The Virtual Cell is a software modeling environment for quantitative cell biological research. Users can create simple or complex multi-layered models with a Java web-based interface. Distinct biological and mathematical frameworks exist within a single graphical interface designed for experimental cell biologists or theoretical biophysicists.
Java Link

The Virtual Cell requires Java.
Get it Now

Run VCell 4.6
Release Date: 6-2-09

New Features in 4.6

Run VCell 4.7 (beta)
Release Date: 6-26-09

New Features in 4.7(beta)

Please Note:
New Users will need to register when they first run the Virtual Cell Software.
Contact Support:
vcell_support@uchc.edu VCell Trouble Shooting

Important information about beta:
The beta version is a pre-release preview of the Virtual Cell software. It is available for testing and feed back purposes. You may choose to use the beta version for new functions that are not yet available in the release version. If you choose to use this version, please send your comments and findings to vcell@uchc.edu


All users of the Virtual Cell are asked to acknowledge NRCAM and NCRR in their publications:
Directions for published Virtual Cell Models


Related Software Projects

Virtual FRAP The Virtual FRAP is a stand alone application for extracting diffusion coefficients and fractional recoveries from photobleaching experiments. Taking advantage of the power of the Virtual Cell modeling environment to do spatial modeling and simulation within realistic experimental geometries, Virtual FRAP uses spatial simulations to obtain best fit parameters directly from image series.

BioNetGen BioNetGen is designed to automatically generate a biochemical reaction network from user-specified rules for biomolecular interactions. BioNetGen is available within Virtual Cell as a web based application and also as a standalone package.

SyBiL The Systems Biology Linker (SyBiL) is a tool to build and annotate models using free web-accessible records of pathways, reactions, substances and literature. SyBiL uses SBPAX (Systems Biology Pathway Exchange), a bridging ontology designed to interlink various formats relevant in Systems Biology, e.g. SBML, VCML and BioPAX. SyBiL will soon be part of the Virtual Cell. The alpha version is available as a stand-alone application exporting SBML and SBPAX.

Gfit Gfit is a program for global (simultaneous) regression analysis of data from different types of experiments. It is particularly useful for studying various systems in Biophysics, Biochemistry and Cell Biology.

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